The Biological Rosetta Stone

  growth1 - tiny   Excluded-Volume - tiny

Our Goal

The genome harbors additional codes. The genetic code was just the first one to be discovered. In order to decipher and decode the genome, we need to make a Biological Rosetta stone. Our research is dedicated to achieving this goal.


To decipher encoding rules, we use an iterative approach, which begins with a model-based design of DNA sequences, synthetic biology experiments, analysis using advanced bioinformatic, thermodynamic, and stochastic models. The results of the experiments and analysis feed-back on the design model, which generates an improved set of sequences until a robust model for the encoding rules is generated.


We design and construct oligo libraries of tens of thousands of synthetic DNA sequences using various numerical approaches.
We use state-of-the-art liquid automated robotics, next generation sequencing  and  time-lapse imaging to carry out our measurements.
We carry out our experiments in vivo in a host of model cell lines: bacteria, yeast, mammalian cell lines.

Open Positions

M.Sc students
Ph.D students
Post-doctoral Scholars
For a new interesting research in our lab (MRG) we are looking for post-doctoral scholars. For more information.
Please send c.v and two recommendations to
or call: +972-77-887-1895


News & Events